Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376285 | 0.81 | CYP3A4 (0.59) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL133880 | 0.81 | CYP3A4 (0.59) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL31173713 | 0.78 | CYP3A4 (0.56) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL11869838 | 0.77 | CYP3A4 (0.55) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL28611992 | 0.77 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1TSHRGABRA1 | |
| SCHEMBL30262874 | 0.77 | CYP3A4 (0.54) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL28927829 | 0.77 | CYP3A4 (0.54) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL28621774 | 0.76 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL15751102 | 0.75 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL314237 | 0.75 | CYP3A4 (0.61) | CYP3A4TRPA1TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799843-B1 | Polyurethane resins containing carbodiimide bonds | NISSHIN SPINNING (JP) | 2003-06-04 | — | — | EP | claimed |
| US-6153718-A | WHEREIN THE DIISOCYANATE COMPONENT COMPRISES: AT LEAST ONE KIND OF UNMODIFIED DIISOCYANATE, AND AT LEAST ONE KIND OF CARBODIIMIDE-MODIFIED DIISOCYANATE | NISSHINBO INDUSTRIES, INC. (JP) | 2000-11-28 | — | — | US | claimed |
| EP-0799843-A1 | Polyurethane resins containing carbodiimide bonds | NISSHINBO INDUSTRIES, INC. (JP) | 1997-10-08 | — | — | EP | claimed |
| EP-0460481-B1 | Process for the stabilisation of resins containing ester groups | BAYER AG (DE) | 1997-04-02 | — | — | EP | claimed |
| US-20240294693-A1 | AROMATIC CARBODIIMIDES, PROCESS FOR THE PREPARATION AND USE THEREOF | LANXESS DEUTSCHLAND GMBH (DE) | 2024-09-05 | — | — | US | disclosed |
| CN-103619900-A | Curable epoxy resin systems containing mixtures of amine hardeners and an excess of epoxide groups | DOW GLOBAL TECHNOLOGIES INC | 2014-03-05 | — | — | CN | disclosed |
| EP-0799843-B1 | Polyurethane resins containing carbodiimide bonds | NISSHIN SPINNING (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6153718-A | WHEREIN THE DIISOCYANATE COMPONENT COMPRISES: AT LEAST ONE KIND OF UNMODIFIED DIISOCYANATE, AND AT LEAST ONE KIND OF CARBODIIMIDE-MODIFIED DIISOCYANATE | NISSHINBO INDUSTRIES, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0799843-A1 | Polyurethane resins containing carbodiimide bonds | NISSHINBO INDUSTRIES, INC. (JP) | 1997-10-08 | — | — | EP | disclosed |
| CN-1028515-C | Method for separating 2, 6-or 3, 5-diethyltoluene from mixture of diethyltoluene isomers | UOP INC (US) | 1995-05-24 | — | — | CN | disclosed |
| CN-1058012-A | Chromatographic separation process for recovering 2, 6-diethyltoluene or 3, 5-diethyltoluene from a mixture containing other Diethyltoluene (DET) isomers | UOP INC (US) | 1992-01-22 | — | — | CN | disclosed |
| CN-85101894-A | The preparation method of polyurethane compositions having low hysteresis | — | 1987-01-17 | — | — | CN | disclosed |