SCHEMBL133880

SCHEMBL133880

CC(C)c1ccc(N=C=O)cc1N=C=O

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.59
TRPA1 O75762 1/20 0.59
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
CYP1A2 P05177 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376285 1.00 CYP3A4 (0.59) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL31173713 0.86 CYP3A4 (0.56) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL112143 0.85 CYP3A4 (0.55) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL28927829 0.84 CYP3A4 (0.54) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL15751102 0.83 CYP3A4 (0.53) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL7591507 0.81 CYP3A4 (0.38) CYP3A4TRPA1TDP1MAPK1ALDH1A1
SCHEMBL11869838 0.81 CYP3A4 (0.55) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL31188371 0.81 CYP3A4 (0.55) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL7186146 0.81 CYP3A4 (0.54) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL30262874 0.81 CYP3A4 (0.54) CYP3A4TRPA1TDP1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2000 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343905-B2 Method for producing cycloolefin resin-decorative molded article RIMTEC CORPORATION (JP) 2025-07-01 US claimed
CN-117279972-A Two-component polyurethane compositions, methods of making, and methods of using the same 阿科玛法国 2023-12-22 CN claimed
EP-4263209-A1 A TWO-COMPONENT POLYURETHANE COMPOSITION, PROCESS FOR PREPARING THE SAME AND A METHOD OF USE THEREOF ARKEMA FRANCE (FR) 2023-10-25 EP claimed
EP-3765562-B1 CARDANOL BLOCKED ISOCYANATE ADHESION PROMOTOR FOR PVC PLASTISOL EVONIK OPERATIONS GMBH (DE) 2023-07-12 EP claimed
CN-113811555-B Urethane (meth) acrylate, neutralized product thereof, photocurable resin composition, and liquid composition 根上工业株式会社 2023-03-10 CN claimed
US-20220396652-A1 MULTI(METH)ACRYLATE-FUNCTIONALIZED OLIGOMERS AND METHODS OF PREPARING AND USING SUCH OLIGOMERS ARKEMA FRANCE (FR) 2022-12-15 US claimed
WO-2022133025-A1 A TWO-COMPONENT POLYURETHANE COMPOSITION, PROCESS FOR PREPARING THE SAME AND A METHOD OF USE THEREOF ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2022-06-23 WO claimed
US-11365313-B2 Cardanol blocked isocyanate adhesion promotor for PVC plastisol EVONIK OPERATIONS GMBH (DE) 2022-06-21 US claimed
CN-114630852-A Poly (meth) acrylate functionalized oligomers and methods of making and using such oligomers 阿科玛法国公司 2022-06-14 CN claimed
CN-108137780-B Preparation of polyamideimides 亨斯迈先进材料许可(瑞士)有限公司 2021-07-30 CN claimed
WO-2008070762-A1 POLYAMIDE POLYOLS AND POLYURETHANES, METHODS FOR MAKING AND USING, AND PRODUCTS MADE THEREFROM ARIZONA CHEMICAL COMPANY (US) 2008-06-12 WO claimed
WO-2007095730-A1 HIGHLY FILLED COMPOSITE MATERIALS CLAUSI ROBERT N (CA) 2007-08-30 WO claimed
US-6930196-B2 Polyurethane hydrogel contact lens NOVARTIS AG (CH) 2005-08-16 US claimed
EP-1549592-A1 OPTICAL FIBER WITH CURED POLYMERIC COATING Pirelli & C. S.p.A. (IT) 2005-07-06 EP claimed
WO-2004031091-A1 OPTICAL FIBER WITH CURED POLYMERIC COATING PIRELLI & C. S.P.A. (IT) 2004-04-15 WO claimed
US-5352527-A Having heat resistant protective layer containing amine-modified polysiloxane, polyisocyanate and reaction product between these RICOH COMPANY, LTD. (JP) 1994-10-04 US claimed
EP-0262472-B1 Electrically insulating material IDEMITSU PETROCHEMICAL CO (JP) 1993-12-22 EP claimed
US-4937305-A Electrically insulating material IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1990-06-26 US claimed
EP-0262472-A2 Electrically insulating material IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-04-06 EP claimed
US-4076945-A Method for making urethane-terminated polycarbodiimides and products thereof THE GENERAL TIRE & RUBBER COMPANY (US) 1978-02-28 US claimed