Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179060 | 0.92 | CYP1A1 (0.44) | CYP1A1CYP1B1RXRAPPARGRARG | |
| SCHEMBL7184066 | 0.86 | TNFRSF1A (0.48) | CYP1A1CYP1B1ABCG2TNFRSF1ATP53 | |
| SCHEMBL7186672 | 0.84 | CYP1A1 (0.50) | CYP1A1CYP1B1DPP4ABCG2MAPT | |
| SCHEMBL7184330 | 0.83 | TNFRSF1A (0.38) | CYP1A1CYP1B1ABCG2KEAP1NFE2L2 | |
| SCHEMBL7191249 | 0.81 | DPP4 (0.45) | CYP1A1CYP1B1DPP4ABCG2KEAP1 | |
| SCHEMBL7187235 | 0.79 | DPP4 (0.42) | CYP1A1CYP1B1DPP4ABCG2KEAP1 | |
| SCHEMBL7192285 | 0.78 | CYP1A1 (0.48) | CYP1A1CYP1B1DPP4ABCG2KEAP1 | |
| SCHEMBL7191537 | 0.78 | ABCG2 (0.40) | CYP1A1CYP1B1DPP4ABCG2KEAP1 | |
| SCHEMBL7184448 | 0.78 | ABCG2 (0.44) | CYP1A1CYP1B1DPP4ABCG2KEAP1 | |
| SCHEMBL7184761 | 0.77 | CYP1A1 (0.47) | CYP1A1CYP1B1DPP4ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |