Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371909 | 1.00 | TDP1 (0.53) | TDP1CYP11B1CYP11B2TNFHTT | |
| Bromide SCHEMBL38655438 | 0.98 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| Boric Acid SCHEMBL28638672 | 0.93 | TDP1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL28708984 | 0.91 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL28363150 | 0.87 | FDPS (0.49) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL10889581 | 0.83 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL7804822 | 0.83 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL10392069 | 0.82 | CYP11B1 (0.40) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL222528 | 0.79 | HTT (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL1344383 | 0.79 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12619008-B2 | Optical halogenated polymer thin film with ultra-high refractive index | UNIVERSITY OF ROCHESTER (US) | 2026-05-05 | — | — | US | claimed |
| CN-117327312-A | High-performance high-proton-conductivity phosphoric acid doped grafted crosslinked membrane and preparation method thereof | 吉林大学 | 2024-01-02 | — | — | CN | claimed |
| CN-110951063-B | Catalyst composition for preparing polyester and preparation method of polyester | 万华化学集团股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-110951063-A | Catalyst composition for preparing polyester and preparation method of polyester | 万华化学集团股份有限公司 | 2020-04-03 | — | — | CN | claimed |
| US-20150202185-A1 | COMPOSITIONS AND METHODS FOR TREATING LYSOSOMAL DISORDERS | TAIJI BIOMEDICAL, INC. | 2015-07-23 | — | — | US | claimed |
| US-20130012539-A1 | Compositions and Methods for Treating Lysosomal Disorders | THE HOSPITAL FOR SICK CHILDREN (CA) | 2013-01-10 | — | — | US | claimed |
| EP-2211856-A1 | COMPOSITIONS AND METHODS FOR TREATING LYSOSOMAL DISORDERS | The Hospital For Sick Children (CA) | 2010-08-04 | — | — | EP | claimed |
| EP-1761587-B1 | PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER | EVONIK ROEHM GMBH (DE) | 2010-01-20 | — | — | EP | claimed |
| US-20100004154-A1 | THERMALLY SENSITIVE POLYMERIC DYE TRANSFER INHIBITOR | BASF SE (DE) | 2010-01-07 | — | — | US | claimed |
| EP-2106413-A1 | THERMALLY SENSITIVE POLYMERIC DYE TRANSFER INHIBITOR | BASF SE (DE) | 2009-10-07 | — | — | EP | claimed |
| WO-1999002155-A1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | ONTOGEN CORPORATION (US) | 1999-01-21 | — | — | WO | claimed |
| EP-0639969-B1 | POLYMERS IN COSMETICS AND PERSONAL CARE PRODUCTS | MINNESOTA MINING & MFG (US) | 1996-06-26 | — | — | EP | claimed |
| EP-0412770-B1 | Polysiloxane-grafted copolymer topical binder composition with novel hydrophilic monomers and method of coating therewith | MINNESOTA MINING & MFG (US) | 1995-10-04 | — | — | EP | claimed |
| US-4933378-A | Fluid loss control additives for oil well cementing compositions | BASF CORPORATION (US) | 1990-06-12 | — | — | US | claimed |
| US-4931489-A | ACRYLAMIDE-VINYL IMIDAZOLE COPOLYMERS AND TERPOLYMERS MIXED WITH WATER AND HYDRAULIC CEMENT | BASF CORPORATION (US) | 1990-06-05 | — | — | US | claimed |
| EP-0342500-A2 | Fluid loss control additives for oil well cementing compositions | BASF Corporation (US) | 1989-11-23 | — | — | EP | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| US-4197220-A | Impregnated metal-polymeric functional beads | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1980-04-08 | — | — | US | claimed |
| US-4123396-A | Impregnated metal-polymeric functional beads | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1978-10-31 | — | — | US | claimed |
| US-3939132-A | Process for the preparation of random copolymers of mono-olefins or of mono-olefins and unconjugated dienes with unsaturated derivatives selected from N-vinylimidazoles and N-vinylimidazolines | SOCIETE NATIONALE DES PETROLES D'AQUITAINE (FR) | 1976-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12619008-B2 | Optical halogenated polymer thin film with ultra-high refractive index | BRI3BP, BRD9, IGF1R | TDP1 3281/4885CYP11B1 4846/4885CYP11B2 4821/4885 |
| US-20130012539-A1 | Compositions and Methods for Treating Lysosomal Disorders | GAA, GBA1, LIPA | TDP1 999/4885CYP11B1 3856/4885CYP11B2 3969/4885 |
| US-20150202185-A1 | COMPOSITIONS AND METHODS FOR TREATING LYSOSOMAL DISORDERS | GAA, GBA1, LIPA | TDP1 999/4885CYP11B1 3856/4885CYP11B2 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.