SCHEMBL7186512

SCHEMBL7186512

O=C1C=C(Cl)C(=O)C=C1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
MEN1 O00255 3/20 0.42
RECQL P46063 3/20 0.42
ALOX12 P18054 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
AURKA O14965 1/20 0.36
AURKB Q96GD4 1/20 0.36
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 2/20 0.35
USP2 O75604 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
GLA P06280 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
BRCA1 P38398 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57290 0.82 MEN1 (0.56) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL169616 0.82 KDM4E (0.43) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL28875633 0.82 KDM4E (0.43) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL28480828 0.78 KDM4E (0.47) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL11135771 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1
Potassium SCHEMBL31397834 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1
Potassium SCHEMBL29990441 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL11411413 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1
Lithium SCHEMBL30194867 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL28391346 0.78 KDM4E (0.42) MAPTKMT2AALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1441637-A Compositions for repelling crawling insects BAYER AG (DE) 2003-09-10 CN disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 MAPT 3240/4885KMT2A 3439/4885ALDH1A1 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.