Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | PDXK | O00764 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12994391 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL18792850 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL18792849 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29883611 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7934019 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL18763024 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL14898738 | 0.81 | GAA (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8089106 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9324747 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7242817 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030060490-A1 | Method for the treatment and prevention of urinary stone disease | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-03-27 | — | — | US | disclosed |
| US-6521645-B2 | Administering pyridoxamine to reduce urinary oxalate concentrations. | THE UNIVERSITY OF KANSAS MEDICAL CENTER | 2003-02-18 | — | — | US | disclosed |
| US-20020115694-A1 | Methods for the treatment and prevention of urinary stone disease | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-22 | — | — | US | disclosed |
| WO-2002039994-A2 | METHODS FOR THE TREATMENT AND PREVENTION OF URINARY STONE DISEASE | UNIVERSITY OF KANSAS MEDICAL CENTER (US) | 2002-05-23 | — | — | WO | disclosed |