Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | PDXK | O00764 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089106 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7242817 | 0.86 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3442567 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL31010835 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL6271143 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29420572 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL4576970 | 0.82 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL31514964 | 0.82 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8027031 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL15128966 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292761-B1 | Pyridoxamine chelating compounds, manganese (II) chelates and their use as NMRI contrast agents | NYCOMED SALUTAR INC (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5130437-A | N,N'-bis-(pyridoxal)ethylenediamine-N,N'-diacetic acid derivatives | SALUTAR, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-4994259-A | Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives | SALUTAR, INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4935518-A | Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof | SALUTAR, INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0292761-A2 | Pyridoxamine chelating compounds, manganese (II) chelates and their use as NMRI contrast agents | NYCOMED SALUTAR, INC. (US) | 1988-11-30 | — | — | EP | disclosed |