Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008178 | 0.90 | HTT (0.55) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL1784666 | 0.83 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL20725735 | 0.83 | HTT (0.56) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL20377399 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL5708996 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL9705945 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL400932 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL5708866 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL1246349 | 0.82 | GPR84 (0.50) | HTTTHRBMAPTSPHK1TSHR | |
| SCHEMBL351276 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586519-B1 | Compounds which exhibit enhanced ultraviolet radiation absorption | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |