Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461572 | 0.74 | — | — | |
| SCHEMBL2355555 | 0.74 | — | — | |
| SCHEMBL9794511 | 0.74 | — | — | |
| SCHEMBL2491298 | 0.74 | — | — | |
| SCHEMBL155959 | 0.70 | — | — | |
| SCHEMBL2142077 | 0.69 | — | — | |
| SCHEMBL8041020 | 0.69 | SLC6A3 (0.33) | HPGDHTT | |
| SCHEMBL28516474 | 0.69 | — | — | |
| SCHEMBL28444711 | 0.67 | — | — | |
| SCHEMBL29037376 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660778-B1 | Silicones which can be emulsified by the method of the invention are, for example, polyorganosiloxane oils, gums or resins | RHODIA CHIMIE (FR) | 2003-12-09 | — | — | US | disclosed |