SCHEMBL7186921

SCHEMBL7186921

C=CC(=O)OC(=O)NC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
TSHR P16473 6/20 0.38
ALDH1A1 P00352 4/20 0.38
FGFR4 P22455 1/20 0.38
CRBN Q96SW2 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743211 0.79 TSHR (0.37) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL9425850 0.77 CRBN (0.45) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL28085865 0.76
SCHEMBL2577481 0.75 TSHR (0.55) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL3761099 0.74 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16143868 0.72 CRBN (0.41) MAPTCACNA1BAPBA1TSHRCRBN
Acrylamide SCHEMBL3363089 0.72 TSHR (0.65) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL2943411 0.72
SCHEMBL27803254 0.71
SCHEMBL28096503 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117180139-A Nail polish gel composition and preparation method thereof 万华化学集团股份有限公司 2023-12-08 CN claimed
US-9580527-B2 Dual cure composite resins containing uretdione and unsaturated sites COVESTRO LLC (US) 2017-02-28 US claimed
US-20160200857-A1 DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND UNSATURATED SITES COVESTRO LLC 2016-07-14 US claimed
WO-2014150712-A1 DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES BAYER MATERIAL SCIENCE LLC (US) 2014-09-25 WO claimed
US-20140275345-A1 DUAL CURE COMPOSITE RESINS CONTAINING URETDIONE AND USATURATED SITES COVESTRO LLC 2014-09-18 US claimed
CN-117180139-A Nail polish gel composition and preparation method thereof 万华化学集团股份有限公司 2023-12-08 CN disclosed
CN-117180139-A Nail polish gel composition and preparation method thereof 万华化学集团股份有限公司 2023-12-08 CN disclosed
US-10883014-B2 Visible light curable coating compositions, articles, and processes of coating articles SDC TECHNOLOGIES, INC. (US) 2021-01-05 US disclosed
US-20190264062-A1 VISIBLE LIGHT CURABLE COATING COMPOSITIONS, ARTICLES, AND PROCESSES OF COATING ARTICLES SDC TECHNOLOGIES, INC. 2019-08-29 US disclosed
CN-105143179-B Polyacrylate allophanates 温科莱斯法国公司 2019-01-08 CN disclosed
CN-105612228-B Photochromic optical articles having allophanate protective coatings and methods of making the same 光学转变公司 2018-03-30 CN disclosed
CN-107022105-A The whips of radiation-hardenable 科思创德国股份有限公司 2017-08-08 CN disclosed
US-9321893-B2 Radiation-curable whipped foams COVESTRO DEUTSCHLAND AG (DE) 2016-04-26 US disclosed
CN-102695736-B Low-viscosity polyurethane acrylate dispersions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-07 CN disclosed
WO-2015054036-A1 PHOTOCHROMIC OPTICAL ARTICLE HAVING ALLOPHANATE PROTECTIVE COATING AND PROCESS FOR MAKING SAME TRANSITIONS OPTICAL, INC. (US) 2015-04-16 WO disclosed
US-20120329895-A1 RADIATION-CURABLE WHIPPED FOAMS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-12-27 US disclosed
US-20120259065-A1 LOW-VISCOSITY POLYURETHANE ACRYLATE DISPERSIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-10-11 US disclosed
CN-1230457-C Compound with isocyanate group, coating composition containing compound, preparation method and application of compound BASF AG (DE) 2005-12-07 CN disclosed
US-6617413-B1 With or without blocking, allophanate groups and free-radically polymerizable C=C double bonds in activated form by a carbonyl group attached directly or an oxygen atom in an ether function BASF AKTIENGESELLSCHAFT (DE) 2003-09-09 US disclosed
CN-1334833-A Coating agents curable by addition to isocyanate groups and radiation-induced addition to activated carbon-carbon covalent double bonds BASF AG (DE) 2002-02-06 CN disclosed