SCHEMBL9425850

SCHEMBL9425850

NC(=O)NC(=O)OC(=O)NC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.45
LMNA P02545 3/20 0.44
TSHR P16473 2/20 0.39
NFKB1 P19838 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
THPO P40225 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA5A P35218 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16143868 0.88 CRBN (0.41) CRBNLMNATSHRNFKB1CYP1A2
Hydrochloric Acid SCHEMBL5583405 0.78
SCHEMBL767374 0.78
SCHEMBL376341 0.78
SCHEMBL8672962 0.78
SCHEMBL7186921 0.77 MAPT (0.41) CRBNLMNATSHRCYP3A4MAPT
SCHEMBL29251273 0.77 CRBN (0.33) CRBNLMNA
SCHEMBL23002881 0.75
SCHEMBL11188380 0.75
SCHEMBL10523966 0.75 TAS2R38 (0.50) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208720-A1 POLYURETHANE GEL AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2018-07-26 US disclosed
CN-1578839-B Modulating urea degradation in wine yeast THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2012-02-08 CN disclosed
CN-1578839-A Modulating urea degradation in wine yeast UNIV BRITISH COLUMBIA (CA) 2005-02-09 CN disclosed
US-5290902-A Polyisocyanates containing allophanate and isocyanurate groups, a process for their production from cyclic diisocyanates and their use in two-component coating compositions MILES INC. (US) 1994-03-01 US disclosed
US-5260483-A Preparation of n-aryl amides from isocyanates DREXEL UNIVERSITY (US) 1993-11-09 US disclosed