SCHEMBL7187046

SCHEMBL7187046

CC1=C2c3c(-c4ccc(C(C)C)cc4)cccc3C1[Zr]C1C(C)=C(c3c(-c4ccc(C(C)C)cc4)cccc31)[Si]2(C)C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7191676 0.88
SCHEMBL1900079 0.85 PDCD1 (0.32)
SCHEMBL7187042 0.85 BRD4 (0.31) BRD4CREBBP
SCHEMBL7188847 0.83 EDNRB (0.36)
Chloromethane SCHEMBL7185377 0.83 PDCD1 (0.30)
SCHEMBL7182751 0.82
SCHEMBL7187056 0.82 BRD4 (0.32) BRD4CREBBP
Hydrochloric Acid SCHEMBL3808738 0.81 BRD4 (0.31) BRD4CREBBP
SCHEMBL7186289 0.81
SCHEMBL7194549 0.79 HSD11B1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed