Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 3/20 | 0.44 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914419 | 0.82 | C1R (0.70) | MAPTKMT2AC1RKLK7KLK14 | |
| SCHEMBL914173 | 0.73 | C1R (0.72) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL914233 | 0.69 | APEX1 (0.67) | ALDH1A1NPSR1KDM4EC1RTSHR | |
| SCHEMBL2281131 | 0.69 | PTGS1 (1.00) | ALDH1A1MAPTPTGS1PTGS2TDP1 | |
| SCHEMBL913515 | 0.69 | C1R (0.62) | ALDH1A1MAPTNPSR1KDM4EPOLB | |
| SCHEMBL14258658 | 0.69 | PTGS1 (0.62) | ALDH1A1MAPTPTGS1PTGS2TSHR | |
| SCHEMBL6565178 | 0.68 | ELANE (0.56) | ALDH1A1MAPTKDM4EKMT2ATDP1 | |
| SCHEMBL2280520 | 0.67 | PTGS1 (0.68) | ALDH1A1MAPTPTGS1PTGS2TDP1 | |
| SCHEMBL5780185 | 0.67 | C1R (1.00) | ALDH1A1MAPTKMT2AC1RKLK7 | |
| SCHEMBL913503 | 0.66 | C1R (0.65) | ALDH1A1KDM4EPOLBKMT2AC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |