SCHEMBL6565178

SCHEMBL6565178

O=c1oc(-c2ccc(-c3nc4ccc(I)cc4c(=O)o3)cc2)nc2ccc(I)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.56
MAPT P10636 6/20 0.53
RAB9A P51151 5/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPC1 O15118 5/20 0.53
RXFP1 Q9HBX9 1/20 0.53
TP53 P04637 2/20 0.49
C1R P00736 5/20 0.49
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
HPN P05981 1/20 0.47
HPGD P15428 1/20 0.46
F2 P00734 1/20 0.45
PLG P00747 1/20 0.45
KLK1 P06870 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564042 0.92 MAPT (0.48) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL12758411 0.86 RAB9A (0.43) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL12758414 0.83 ALDH1A1 (0.49) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL6565665 0.80 TP53 (0.70) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL2333007 0.80 RAB9A (0.69) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL2328301 0.80 ALDH1A1 (0.63) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL2539367 0.80 MAPT (0.77) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL15436209 0.79 RAB9A (0.75) ELANEMAPTRAB9AMEN1KMT2A
SCHEMBL914419 0.78 C1R (0.70) ELANEMAPTMEN1KMT2AC1R
SCHEMBL3539033 0.78 ELANE (0.70) ELANEMEN1KMT2AC1RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed