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SCHEMBL7187562

SCHEMBL7187562

CCCOc1cc(OCCC)c(PC(=O)c2c(C)cc(C)c(C)c2C)c(OCCC)c1.[LiH]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 5/20 0.35
▸ THRA P10827 1/20 0.35
▸ ELANE P08246 2/20 0.33
▸ SLC5A1 P13866 1/20 0.33
▸ SLC5A2 P31639 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ KAT6A Q92794 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ HTT P42858 1/20 0.32
▸ KDM4E B2RXH2 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ PPARG P37231 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177978 0.94 THRB (0.39) THRBTHRAELANESMN1; SMN2KDM4E
SCHEMBL7185554 0.93 THRB (0.44) THRBTHRATSHR
SCHEMBL7175225 0.92 THRB (0.46) THRBTHRATSHR
SCHEMBL7183625 0.89 FFAR1 (0.34) THRBTHRALMNAKMT2AMAPT
SCHEMBL7181317 0.89 TDP1 (0.32) THRBTHRAL3MBTL1
SCHEMBL7174748 0.87 ELANE (0.38) THRBTHRAELANESLC5A1SLC5A2
SCHEMBL7189372 0.87 KDM4E (0.37) SLC5A1SLC5A2KMT2ASMN1; SMN2MAPT
SCHEMBL7190283 0.87 MAPK1 (0.36) THRBTHRASMN1; SMN2HTTKDM4E
SCHEMBL7180884 0.84 MAPT (0.37) SLC5A1SLC5A2LMNAKMT2AL3MBTL1
SCHEMBL7188781 0.84 MAPT (0.35) THRBTHRAELANESLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 THRB 2119/4885THRA 1901/4885ELANE 4357/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 THRB 2521/4885THRA 2159/4885ELANE 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.