Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131295 | 1.00 | MAPT (0.62) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL4156173 | 1.00 | MAPT (0.62) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL11833372 | 0.91 | CYP2C19 (0.58) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL11833367 | 0.91 | CYP2C19 (0.58) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL18780435 | 0.90 | MAPT (0.61) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL19991845 | 0.87 | PARP10 (0.59) | MAPTRECQLCYP2C19HSD17B10CYP3A4 | |
| SCHEMBL16131296 | 0.84 | CYP1B1 (0.75) | MAPTRECQLCYP3A4TDP1HDAC1 | |
| SCHEMBL27494989 | 0.84 | CYP1B1 (0.75) | MAPTRECQLCYP3A4TDP1HDAC1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28483617 | 0.84 | HDAC1 (0.61) | MAPTRECQLCYP2C19TDP1HDAC1 | |
| SCHEMBL16131294 | 0.83 | CYP1B1 (0.72) | MAPTRECQLCYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864185-A | β-phosphono enamine derivates and preparation method thereof | 苏州大学 | 2018-11-23 | — | — | CN | claimed |
| CN-108727428-A | Beta-amino phosphonate derivative and preparation method thereof | 苏州大学 | 2018-11-02 | — | — | CN | claimed |
| US-6586184-B2 | Rearranging target nucleotide sequences; obtain cells, transfor with nucleotide sequences, detecting nucleotide sequences adjustment in prokaryotic cell | VALIGEN (U.S.), INC. | 2003-07-01 | — | — | US | claimed |
| US-20020151072-A1 | Chimeric mutational vectors | VALIGEN (U.S), INC. | 2002-10-17 | — | — | US | claimed |
| EP-1078097-A4 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | KIMERAGEN INC (US) | 2002-06-05 | — | — | EP | claimed |
| EP-1084272-A4 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | KIMERAGEN INC (US) | 2002-03-13 | — | — | EP | claimed |
| US-6211351-B1 | FOR INTRODUCTION OF GENETIC CHANGES IN EUKARYOTIC CELLS | VALIGEN (US), INC. | 2001-04-03 | — | — | US | claimed |
| EP-1084272-A1 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | Kimeragen Inc. (US) | 2001-03-21 | — | — | EP | claimed |
| EP-1078097-A1 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | Kimeragen Inc. (US) | 2001-02-28 | — | — | EP | claimed |
| US-6010907-A | TRANSFORMING TARGET DNA SEQUENCES | KIMERAGEN, INC. (US) | 2000-01-04 | — | — | US | claimed |
| US-6004804-A | 3'-EXONUCLEASE PROTECTED DUPLEX MUTATIONAL VECTORS; USED TO MAKE SPECIFIC GENETIC ALTERATIONS IN THE GENOME AND IN PLASMIDS OF TARGET PROKARYOTIC CELLS | KIMERAGEN, INC. (US) | 1999-12-21 | — | — | US | claimed |
| WO-1999058702-A1 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | KIMERAGEN, INC. (US) | 1999-11-18 | — | — | WO | claimed |
| WO-1999058723-A1 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | KIMERAGEN, INC. (US) | 1999-11-18 | — | — | WO | claimed |
| CN-107325018-B | β-trifluoromethyl enamine derivates and preparation method thereof | 苏州大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-107325018-A | β trifluoromethyl enamine derivates and preparation method thereof | 苏州大学 | 2017-11-07 | — | — | CN | disclosed |
| US-5556913-A | CURABLE CATIONIC POLYMERS TO FORM FILMS | NIPPON PAINT CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5011981-A | Novel peroxide monomer and a polymer therefrom | NIPPON PAINT CO., LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0413351-A2 | Aqueous dispersion coating composition | Nippon Paint Co., Ltd. (JP) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413352-A2 | Solvent based coating composition | Nippon Paint Co., Ltd. (JP) | 1991-02-20 | — | — | EP | disclosed |
| EP-0294237-A2 | Novel peroxide monomer and a polymer therefrom | Nippon Paint Co., Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |