Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194232 | 0.96 | EDNRB (0.33) | EDNRBEDNRA | |
| SCHEMBL7191351 | 0.94 | HSD17B10 (0.35) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL7184015 | 0.94 | HSD17B10 (0.32) | TLR8DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL7194423 | 0.94 | HSD17B10 (0.34) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL7194525 | 0.94 | HSD17B10 (0.34) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL7189785 | 0.92 | HSD17B10 (0.35) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL7189564 | 0.91 | HSD17B10 (0.34) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL7187654 | 0.91 | HSD11B1 (0.35) | TLR8DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL7194272 | 0.91 | EDNRB (0.34) | EDNRBEDNRA | |
| SCHEMBL7191693 | 0.90 | GCGR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054911-B1 | CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | claimed |