Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400709 | 0.85 | HMGB1 (0.65) | HMGB1ALBKDM4EALDH1A1HPGD | |
| SCHEMBL3899554 | 0.84 | FOLH1 (0.59) | HMGB1ALDH1A1FOLH1BIDMCL1 | |
| SCHEMBL300854 | 0.83 | HMGB1 (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| Hydrochloric Acid SCHEMBL7539402 | 0.83 | FOLH1 (0.58) | HMGB1ALDH1A1FOLH1BIDMCL1 | |
| SCHEMBL1257329 | 0.83 | FOLH1 (0.58) | HMGB1ALDH1A1FOLH1BIDMCL1 | |
| SCHEMBL6435540 | 0.82 | BID (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| SCHEMBL2044839 | 0.82 | BID (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| SCHEMBL1003208 | 0.82 | BID (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| SCHEMBL5272270 | 0.82 | BID (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| SCHEMBL6436998 | 0.82 | BID (0.63) | HMGB1KDM4EHSD17B10MMP2BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, HACL2 | HMGB1 3401/4885ALB 2308/4885KDM4E 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.