SCHEMBL7187766

SCHEMBL7187766

COCCN(C)C(=O)C1=C[N+](C)(c2cncn2Cc2ccc(C#N)cc2)C=C1c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 5/20 0.45
FNTB P49356 5/20 0.45
PGGT1B P53609 4/20 0.45
HTR2C P28335 1/20 0.40
CYP11B1 P15538 3/20 0.40
CYP11B2 P19099 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7138881 0.91 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP11B1
SCHEMBL7185960 0.91 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP11B1
SCHEMBL8162712 0.91 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP11B1
SCHEMBL7066746 0.88 FNTA (0.47) FNTAFNTBPGGT1BHTR2CCYP11B1
SCHEMBL7083958 0.86 HTR2C (0.45) FNTAFNTBPGGT1BHTR2C
SCHEMBL7084009 0.86 FNTA (0.43) FNTAFNTBPGGT1BHTR2C
SCHEMBL6972936 0.82 HTR2C (0.41) FNTAFNTBPGGT1BHTR2C
SCHEMBL7083084 0.77 FNTA (0.47) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7084532 0.77 FNTA (0.56) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL6926980 0.77 FNTA (0.73) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045846-B1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD (KR) 2003-05-02 EP disclosed