Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.46 |
| ▸ | FNTB | P49356 | 8/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162712 | 0.93 | FNTA (0.46) | FNTAFNTBPGGT1BHTR2CCYP11B1 | |
| SCHEMBL7138881 | 0.93 | FNTA (0.46) | FNTAFNTBPGGT1BHTR2CCYP11B1 | |
| SCHEMBL7187766 | 0.91 | FNTA (0.45) | FNTAFNTBPGGT1BHTR2CCYP11B1 | |
| SCHEMBL7066746 | 0.90 | FNTA (0.47) | FNTAFNTBPGGT1BHTR2CCYP11B1 | |
| SCHEMBL7083958 | 0.88 | HTR2C (0.45) | FNTAFNTBPGGT1BHTR2CUSP1 | |
| SCHEMBL7084009 | 0.88 | FNTA (0.43) | FNTAFNTBPGGT1BHTR2CUSP1 | |
| SCHEMBL6972936 | 0.84 | HTR2C (0.41) | FNTAFNTBPGGT1BHTR2CUSP1 | |
| SCHEMBL7087362 | 0.79 | FNTA (0.48) | FNTAFNTBPGGT1BHTR2CCYP11B1 | |
| SCHEMBL7087340 | 0.79 | FNTA (0.59) | FNTAFNTBPGGT1BHTR2C | |
| SCHEMBL7080004 | 0.76 | FNTA (0.58) | FNTAFNTBPGGT1BHTR2CCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |