SCHEMBL7187883

SCHEMBL7187883

Nc1cccc(Oc2ccc(N)cc2Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.55
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47
NLRP1 Q9C000 1/20 0.47
NOD2 Q9HC29 1/20 0.47
PDE7A Q13946 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633144 0.89 MAOB (0.52) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL2529649 0.89 MRGPRX4 (0.51) MAOBMAPTALDH1A1CYP3A4SMN1; SMN2
SCHEMBL4962329 0.89 MRGPRX4 (0.59) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL3509042 0.88 MAOB (0.59) MAOBMAPTALDH1A1CYP3A4SMN1; SMN2
SCHEMBL30617019 0.87 CYP3A4 (0.58) MAOBMAPTALDH1A1CYP3A4SMN1; SMN2
SCHEMBL10815534 0.87 MAOB (0.57) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL1374919 0.87 CYP3A4 (0.58) MAOBMAPTALDH1A1CYP3A4SMN1; SMN2
SCHEMBL29865080 0.86 SMN1; SMN2 (0.60) MAPTPOLBALDH1A1CYP3A4SMN1; SMN2
SCHEMBL3126923 0.86 EGFR (0.47) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL3130003 0.86 L3MBTL1 (0.63) MAOBMAPTALDH1A1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed
WO-1997013745-A1 HIGH TEMPERATURE EPOXY RESINS THE SECRETARY OF STATE FOR DEFENCE (GB) 1997-04-17 WO disclosed