Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189189 | 1.00 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1CA2 | |
| SCHEMBL69831 | 0.97 | — | — | |
| Alcohol SCHEMBL11224298 | 0.84 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1CA2 | |
| Alcohol SCHEMBL1847595 | 0.84 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1CA2 | |
| Alcohol SCHEMBL11224304 | 0.84 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1CA2 | |
| Ethylene Glycol SCHEMBL28316673 | 0.84 | MEN1 (0.53) | MEN1KMT2ATSHRMAPK1CA2 | |
| Methyl Alcohol SCHEMBL9063376 | 0.83 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1CA2 | |
| SCHEMBL23647292 | 0.83 | CA2 (0.44) | MEN1KMT2ATSHRMAPK1CA2 | |
| SCHEMBL5668460 | 0.83 | CA2 (0.44) | MEN1KMT2ATSHRMAPK1CA2 | |
| SCHEMBL10835191 | 0.83 | CA2 (0.44) | MEN1KMT2ATSHRMAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174489-A1 | Process for preparing cutting lubricant fluids | Nueva Fl Ibérica, S.A. (ES) | 2002-01-23 | — | — | EP | claimed |
| EP-1343769-B1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7312328-B2 | Benzoylpyridazines | MERCK PATENT GMBH (DE) | 2007-12-25 | — | — | US | disclosed |
| EP-0697814-B1 | POUR-ON FORMULATIONS CONTAININNG POLYMERIC MATERIAL, GLYCOLS AND GLYCERIDES | MERCK & CO INC (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-1174489-A1 | Process for preparing cutting lubricant fluids | Nueva Fl Ibérica, S.A. (ES) | 2002-01-23 | — | — | EP | disclosed |
| US-5516761-A | AVERMECTIN COMPOUND USED TO TREAT ECTO- AND ENDOPARASITES IN ANIMALS | MERCK & CO., INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0697814-A1 | POUR-ON FORMULATIONS CONTAININNG POLYMERIC MATERIAL, GLYCOLS AND GLYCERIDES | MERCK & CO. INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026113-A2 | POUR-ON FORMULATIONS CONTAININNG POLYMERIC MATERIAL, GLYCOLS AND GLYCERIDES | MERCK & CO., INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0193347-B1 | 13-SUBSTITUTED DERIVATIVES OF AVERMECTIN AGLYCONES | MERCK & CO. INC. (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0193347-A2 | 13-Substituted derivatives of avermectin aglycones | MERCK & CO. INC. (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4587247-A | ANTHELMINTIC, PARASITICIDES | MERCK & CO., INC. (US) | 1986-05-06 | — | — | US | disclosed |