SCHEMBL7188835

SCHEMBL7188835

O=C1OC(=O)C2CCC(c3ccccc3)=CC12

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
F2R P25116 3/20 0.33
ALDH2 P05091 1/20 0.32
PTGS2 P35354 2/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188841 1.00 KMT2A (0.33) KMT2AF2RALDH2PTGS2ALDH1A1
SCHEMBL7188829 1.00 KMT2A (0.33) KMT2AF2RALDH2PTGS2ALDH1A1
Biphenyl SCHEMBL28193786 0.72 KMT2A (0.33) KMT2AF2RALDH2ALDH1A1
SCHEMBL9450413 0.72
SCHEMBL7173427 0.72 TAS2R46 (0.39) KMT2AF2R
SCHEMBL7188891 0.72 TAS2R46 (0.39) KMT2AF2R
SCHEMBL9450292 0.72
SCHEMBL7190172 0.72
SCHEMBL7190177 0.72
SCHEMBL216911 0.72 TAS2R46 (0.39) KMT2AF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed