SCHEMBL7188850

SCHEMBL7188850

CCc1ccc(-c2cccc3c2C=C(C)C3C[SiH]([Zr])CC2C(C)=Cc3c(-c4ccc(CC)cc4)cccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7186293 0.90
SCHEMBL7194551 0.88 HSD11B1 (0.35)
SCHEMBL7189480 0.87 EDNRB (0.33) EDNRBEDNRA
SCHEMBL22567806 0.87 PDCD1 (0.34) PDCD1CD274
SCHEMBL7193708 0.86 RARB (0.37)
SCHEMBL7194278 0.84 EDNRB (0.32) EDNRBEDNRA
SCHEMBL7187051 0.84 BRD4 (0.33)
SCHEMBL7191678 0.83
SCHEMBL7194238 0.82 EDNRB (0.31) EDNRBEDNRA
SCHEMBL8402356 0.82 EDNRB (0.34) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed