SCHEMBL7188940

SCHEMBL7188940

CCC1=Cc2c(-c3ccccc3)cccc2C1C[SiH]([Zr])CC1C(CC)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189480 0.90 EDNRB (0.33)
SCHEMBL7187133 0.90
SCHEMBL7187045 0.86 BRD4 (0.32)
SCHEMBL7194492 0.86
SCHEMBL8682615 0.85 PDCD1 (0.32)
SCHEMBL7644720 0.84 PDCD1 (0.33)
SCHEMBL4620494 0.84 PDCD1 (0.33)
SCHEMBL7193721 0.84
SCHEMBL7189796 0.84 RARB (0.34)
SCHEMBL22567806 0.83 PDCD1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583227-B2 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-24 US disclosed
US-20020160914-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-10-31 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed