Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644720 | 0.91 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL8682615 | 0.88 | PDCD1 (0.32) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL5426467 | 0.87 | PDCD1 (0.31) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL3818126 | 0.87 | PDCD1 (0.31) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL4001907 | 0.85 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL6890535 | 0.84 | BRD4 (0.35) | BRD4 | |
| SCHEMBL7188940 | 0.84 | — | — | |
| SCHEMBL7200922 | 0.84 | ADORA3 (0.32) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL5859122 | 0.83 | PDCD1 (0.34) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL6649301 | 0.81 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20020052446-A1 | Composition based on monofluorometal complexes | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | US | disclosed |