Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190389 | 0.99 | TLR8 (0.43) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL7191432 | 0.99 | TLR8 (0.43) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL7194266 | 0.99 | TLR8 (0.43) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL1606156 | 0.99 | TLR8 (0.43) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL7202011 | 0.96 | TLR8 (0.42) | TLR8CNR1CNR2GAA | |
| SCHEMBL1990277 | 0.81 | TLR8 (0.44) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL1994553 | 0.80 | CNR1 (0.45) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL7549186 | 0.80 | CNR1 (0.45) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL8915572 | 0.80 | CNR1 (0.45) | TLR8CNR1NR1H2NR1H3LIPG | |
| SCHEMBL1990197 | 0.80 | CNR1 (0.45) | TLR8CNR1NR1H2NR1H3LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| US-6147035-A | DETERGENCY; HEAT AND OXIDATION RESISTANCE; REDUCE NITROGEN OXIDE EMISSION | TONEN CORPORATION (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0778334-A1 | HEAT-RESISTANT LUBRICATING OIL COMPOSITION | Tonen Corporation (JP) | 1997-06-11 | — | — | EP | disclosed |