SCHEMBL1990277

SCHEMBL1990277

CCCCCc1ccccc1-c1ccc2ccccc2c1N

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 11/20 0.44
CNR1 P21554 2/20 0.44
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989997 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL8915572 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL7547478 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL1990197 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL1678984 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL1994553 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL7549186 0.99 CNR1 (0.45) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL1992947 0.95 TLR8 (0.43) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL17554803 0.88 CNR1 (0.44) TLR8CNR1KDM4EUSP2ALDH1A1
SCHEMBL6768325 0.83 TLR8 (0.50) TLR8KDM4EUSP2ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230166635-A1 MONITORING HEALTH OF HEAT TRANSFER FLUIDS FOR ELECTRIC SYSTEMS ExxonMobil Technology and Engineering Company (US) 2023-06-01 US disclosed
US-9359573-B2 Migration of air release in lubricant base stocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-07 US disclosed
EP-2055764-B1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD AND USE OF THE LUBRICANT AOKI SCIENCE INST CO LTD (JP) 2014-10-15 EP disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-8728994-B2 Oil type lubricant for forging, forging method and spray apparatus AOKI SCIENCE INSTITUTE CO., LTD. (JP) 2014-05-20 US disclosed
US-20140038867-A1 MIGRATION OF AIR RELEASE IN LUBRICANT BASE STOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-02-06 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090286455-A1 METHOD FOR SIZING SINTERED METAL IDEMITSU KOSAN CO., LTD. (JP) 2009-11-19 US disclosed
US-20090118149-A1 Oil Type Lubricant for Forging, Forging Method and Spray Apparatus AOKI SCIENCES INSTITUTE CO.,LTD. (JP) 2009-05-07 US disclosed
EP-2055764-A1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD, AND COATING APPARATUS Aoki Science Institute Co, Ltd (JP) 2009-05-06 EP disclosed
US-20060252659-A1 Lubricating oil for dynamic fluid-pressure bearing, dynamic-fluid-pressure bearing, motor, and information recording/reproducing apparatus SEIKO INSTRUMENTS, INC. (JP) 2006-11-09 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed