SCHEMBL7189323

SCHEMBL7189323

CCCCCOC(=O)CC=Cc1ccc(Oc2c(-c3ccc(O)cc3)ccc3cc(O)ccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 19/20 0.49
ESR2 Q92731 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7193982 0.91 ESR1 (0.48) ESR1ESR2
SCHEMBL7187968 0.90 ESR1 (0.50) ESR1ESR2
SCHEMBL7194281 0.87 ESR1 (0.55) ESR1ESR2
SCHEMBL7182803 0.85 ESR1 (0.54) ESR1ESR2
SCHEMBL7186984 0.83 ESR1 (0.51) ESR1ESR2
SCHEMBL7186980 0.83 ESR1 (0.51) ESR1ESR2
SCHEMBL7193881 0.83 ESR1 (0.46) ESR1ESR2
SCHEMBL7186036 0.82 ESR1 (0.49) ESR1ESR2
SCHEMBL7195079 0.82 ESR1 (0.49) ESR1ESR2
SCHEMBL7189521 0.82 ESR1 (0.46) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835867-B1 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods LILLY CO ELI (US) 2003-12-03 EP claimed