SCHEMBL718943

SCHEMBL718943

C=CCCCCC[SiH](OC)OC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 4/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 3/20 0.35
ABCC4 O15439 1/20 0.35
LPAR3 Q9UBY5 2/20 0.35
LPAR2 Q9HBW0 1/20 0.35
TRPA1 O75762 2/20 0.33
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383501 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037411 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8513733 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037443 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8512472 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8511561 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037316 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8512216 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL3339190 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL29384177 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863146-B1 Method of making organosilicon carbonyl compounds DOW CORNING (US) 2003-02-19 EP claimed
US-6126777-A AN AQUEOUS ADHESIVE USEFUL FOR BONDING VULCANIZABLE ELASTOMERIC RUBBER TO A SUBSTRATE, MADE FROM ALTEST ONE VINYL GROUP CONTAINING SILANE COMPOUND AND A POLYISOCYANATE; VULCANIZABLE; CURING; INCREASED SHELF-LIFE LORD CORPORATION (US) 2000-10-03 US claimed
US-5880304-A Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1999-03-09 US claimed
EP-0863146-A2 Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1998-09-09 EP claimed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
US-12045007-B2 Toner additives comprising composite particles CABOT CORPORATION (US) 2024-07-23 US disclosed
CN-115348990-B Composition for liquid-based additive manufacturing 卡博特公司 2024-06-04 CN disclosed
CN-117777543-A Composition for liquid-based additive manufacturing 卡博特公司 2024-03-29 CN disclosed
US-20230100957-A1 Composition for Liquid-Based Additive Manufacturing CABOT CORPORATION 2023-03-30 US disclosed
EP-4100469-A1 COMPOSITION FOR LIQUID-BASED ADDITIVE MANUFACTURING Cabot Corporation (US) 2022-12-14 EP disclosed
CN-115348990-A Compositions for liquid-based additive manufacturing 卡博特公司 2022-11-15 CN disclosed
WO-2021158636-A1 COMPOSITION FOR LIQUID-BASED ADDITIVE MANUFACTURING CABOT CORPORATION (US) 2021-08-12 WO disclosed
EP-0691363-B1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING (US) 1997-09-03 EP disclosed
US-5502107-A IMPACT STRENGTH DOW CORNING CORPORATION (US) 1996-03-26 US disclosed
EP-0691363-A1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING CORPORATION (US) 1996-01-10 EP disclosed
EP-0690101-A2 Functional polyorganosiloxane emulsions from silanes having two hydrolysable functional groups and photocurable compositions therefrom DOW CORNING CORPORATION (US) 1996-01-03 EP disclosed
US-5449716-A Curable composition of silane and polysiloxanes with catalyst DOW CORNING CORPORATION (US) 1995-09-12 US disclosed
EP-0280423-B1 HEAT ACTIVATED SILICON-BASED ADHESIVE LORD CORPORATION (US) 1992-08-12 EP disclosed
EP-0280423-A2 Heat activated silicon-based adhesive LORD CORPORATION (US) 1988-08-31 EP disclosed
US-4690966-A BLEND OF OLEFINIC ORGANOSILANE, WATER AND ALUMINO ZIRCONIUM COMPLEX LORD CORPORATION (US) 1987-09-01 US disclosed