SCHEMBL8513733

SCHEMBL8513733

C=CCCCCCC[SiH](OC)OC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 4/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 3/20 0.35
ABCC4 O15439 1/20 0.35
LPAR3 Q9UBY5 2/20 0.35
LPAR2 Q9HBW0 1/20 0.35
TRPA1 O75762 2/20 0.33
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383501 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037411 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037443 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8512472 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8511561 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL6037316 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL8512216 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL3339190 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL718943 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4
SCHEMBL29384177 1.00 TSHR (0.46) TSHRALDH1A1LMNAMAPTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12091512-B2 Organopolysiloxane and coating composition containing organopolysiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-09-17 US disclosed
EP-4074753-B1 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE SHINETSU CHEMICAL CO (JP) 2023-12-13 EP disclosed
US-20220340715-A1 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-10-27 US disclosed
CN-115216020-A Organopolysiloxane and coating composition containing organopolysiloxane 信越化学工业株式会社 2022-10-21 CN disclosed
EP-4074753-A2 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE Shin-Etsu Chemical Co., Ltd. (JP) 2022-10-19 EP disclosed
WO-2022078046-A1 POLYMER HAVING DISPERSING FUNCTION, POLYCARBOXYLIC ACID CEMENT DISPERSANT, PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-04-21 WO disclosed
WO-2022033588-A1 POLYMER HAVING DISPERSING FUNCTION, OIL WELL CEMENT DISPERSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2022-02-17 WO disclosed
US-20120136082-A1 BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS WACKER CHEMIE AG (DE) 2012-05-31 US disclosed
CN-100410262-C Organic silicon compound containing phosphorus and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-08-13 CN disclosed
CN-1944446-A Organic silicon compound containing phosphorus and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2007-04-11 CN disclosed