Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1961387 | 0.87 | HTR7 (0.48) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL144326 | 0.75 | KMT2A (0.65) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL28621243 | 0.74 | BCHE (0.51) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL27575643 | 0.74 | KMT2A (0.48) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL367886 | 0.72 | KMT2A (0.61) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL3503936 | 0.71 | MAPT (0.56) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL4402923 | 0.71 | POLB (0.71) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL30341829 | 0.71 | POLB (0.71) | POLBKMT2AMEN1LMNAGAA | |
| Hydrochloric Acid SCHEMBL29012769 | 0.70 | KMT2A (0.59) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL29273709 | 0.70 | MAPT (0.65) | KMT2AMEN1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6593084-B2 | Carcinogen assay | Bird, Robert E. | 2003-07-15 | — | — | US | disclosed |
| US-20020086288-A1 | CARCINOGEN ASSAY | BIRD, ROBERT E. | 2002-07-04 | — | — | US | disclosed |
| EP-1121466-A1 | CARCINOGEN ASSAY | Bioreliance Testing and Development, Inc. (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000022168-A9 | CARCINOGEN ASSAY | MA BIOSERVICES INC (US) | 2000-09-14 | — | — | WO | disclosed |
| WO-2000022168-A1 | CARCINOGEN ASSAY | BIORELIANCE TESTING AND DEVELOPMENT, INC. (US) | 2000-04-20 | — | — | WO | disclosed |