Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189637 | 1.00 | ABCG2 (0.42) | ABCG2MAOBCAPN1CTSLCTSB | |
| SCHEMBL9206266 | 0.97 | ABCG2 (0.40) | ABCG2MAOBCAPN1CTSLCTSB | |
| SCHEMBL9206270 | 0.97 | ABCG2 (0.40) | ABCG2MAOBCAPN1CTSLCTSB | |
| SCHEMBL7190869 | 0.91 | CA1 (0.41) | ABCG2CTSLCTSBMAPTRAB9A | |
| SCHEMBL7190872 | 0.91 | CA1 (0.41) | ABCG2CTSLCTSBMAPTRAB9A | |
| SCHEMBL7183732 | 0.90 | ABCG2 (0.43) | ABCG2MAOBCAPN1CTSLCTSB | |
| SCHEMBL7183727 | 0.90 | ABCG2 (0.43) | ABCG2MAOBCAPN1CTSLCTSB | |
| SCHEMBL7806545 | 0.89 | CYP3A4 (0.36) | ABCG2MAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL7189262 | 0.89 | CYP3A4 (0.36) | ABCG2MAPTRAB9AMEN1ALDH1A1 | |
| SCHEMBL7179097 | 0.87 | CTSL (0.47) | ABCG2MAOBCAPN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |