⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029777 | 0.79 | — | — | |
| SCHEMBL7872543 | 0.79 | CES2 (0.32) | — | |
| SCHEMBL28263200 | 0.79 | — | — | |
| SCHEMBL2395260 | 0.79 | — | — | |
| SCHEMBL1201615 | 0.79 | CES2 (0.34) | — | |
| SCHEMBL3417704 | 0.77 | — | — | |
| SCHEMBL2000512 | 0.77 | CES2 (0.33) | — | |
| SCHEMBL31258565 | 0.76 | — | — | |
| SCHEMBL4445676 | 0.76 | — | — | |
| SCHEMBL2016761 | 0.76 | EIF4A3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101525270-B | 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof | YUANXIN TECHNOLOGY MATERIALS CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-101525271-B | Preparation method of 1, 4-bis (difluoromethyl) tetrafluorobenzene | YUANXIN TECHNOLOGY MATERIALS CO LTD | 2011-09-07 | — | — | CN | disclosed |
| CN-101525270-A | 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof | YUANXIN TECHNOLOGY MATERIALS C | 2009-09-09 | — | — | CN | disclosed |
| CN-101525271-A | Preparation method of 1, 4-bis (difluoromethyl) tetrafluorobenzene | YUANXIN TECHNOLOGY MATERIALS C | 2009-09-09 | — | — | CN | disclosed |
| EP-0908438-B1 | Process for the preparation of 2,3,4,5-tetrafluorobenzene derivatives | BAYER AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6613948-B1 | Reacting the corresponding chlorobenzene or (chloro, fluoro)-benzene derivatives with potassium fluoride in solvent; distillation; tetrachloro benzotrifluoride, -benzoyl fluoride, or -benzonitrile as starting materials | BAYER AG (DE) | 2003-09-02 | — | — | US | disclosed |
| EP-0908438-A2 | Process for the preparation of 2,3,4,5-tetrafluorobenzene derivatives | BAYER AG (DE) | 1999-04-14 | — | — | EP | disclosed |
| EP-0006354-B1 | FLUORO-SUBSTITUTED PYRETHROID-TYPE ESTERS, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES FOR USE IN SUCH PROCESSES, COMPOSITIONS FOR INSECTICIDAL USE, AND METHODS OF COMBATING INSECT PESTS | ICI AUSTRALIA LIMITED (AU) | 1984-09-26 | — | — | EP | disclosed |
| US-4376784-A | Pesticidal fluorinated esters of the pyrethrin or pyrethroid type | ICI AUSTRALIA LIMITED (AU) | 1983-03-15 | — | — | US | disclosed |
| US-4283414-A | Pesticidal fluorinated esters of the pyrethrin or pyrethroid type | ICI AUSTRALIA LIMITED (AU) | 1981-08-11 | — | — | US | disclosed |
| EP-0006354-A1 | Fluoro-substituted pyrethroid-type esters, processes for their preparation, intermediates for use in such processes, compositions for insecticidal use, and methods of combating insect pests | ICI AUSTRALIA LIMITED (AU) | 1980-01-09 | — | — | EP | disclosed |