Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660441 | 0.76 | XDH (0.47) | SIRT1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL29105383 | 0.75 | NPC1 (0.63) | PTPN1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL5597840 | 0.73 | CYP3A4 (0.54) | MEN1GAAKMT2ACYP19A1KDM4E | |
| SCHEMBL30641816 | 0.72 | CYP19A1 (0.58) | CYP19A1MAOBCA1CA7CA9 | |
| SCHEMBL12068876 | 0.70 | ABCG2 (0.65) | PTPN1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL29139205 | 0.70 | IDO1 (0.40) | MEN1KMT2ACYP19A1KDM4ECA1 | |
| SCHEMBL28141209 | 0.68 | CYP19A1 (0.54) | CYP19A1ABCG2ABCB1MAOBDNMT3B | |
| SCHEMBL5146606 | 0.68 | POLB (0.60) | MEN1KMT2ACYP19A1NPC1RAB9A | |
| SCHEMBL23752214 | 0.68 | CYP19A1 (0.51) | PTPN1MEN1KMT2ACYP19A1KDM4E | |
| SCHEMBL2396876 | 0.68 | MAPT (0.51) | MEN1KMT2AL3MBTL1CYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102049010-B | Medicament for preventing and treating ischemic cerebrovascular diseases | JIANFENG SU | 2012-07-04 | — | — | CN | disclosed |
| CN-102049010-A | Medicament for preventing and treating ischemic cerebrovascular diseases | JIANFENG SU | 2011-05-11 | — | — | CN | disclosed |
| US-20030152588-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-08-14 | — | — | US | disclosed |