SCHEMBL7190503

SCHEMBL7190503

Nc1cc(N)c(Cl)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.70
KDM4E B2RXH2 5/20 0.59
TDP1 Q9NUW8 4/20 0.59
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
MAPT P10636 3/20 0.50
THRB P10828 2/20 0.50
RECQL P46063 2/20 0.50
POLB P06746 2/20 0.50
USP2 O75604 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50
BLM P54132 1/20 0.50
MCL1 Q07820 1/20 0.50
ALDH1A1 P00352 7/20 0.45
CASP1 P29466 3/20 0.45
CASP7 P55210 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP2C19 P33261 2/20 0.45
TNF P01375 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31396152 1.00 CYP3A4 (0.70) CYP3A4KDM4ETDP1KMT2AMEN1
SCHEMBL2810897 0.89 CYP3A4 (0.59) CYP3A4KDM4ETDP1KMT2AMEN1
SCHEMBL2810225 0.86 CYP3A4 (0.57) CYP3A4KDM4ETDP1KMT2AMEN1
Chloramben SCHEMBL117283 0.83 CYP3A4 (1.00) CYP3A4KDM4ETDP1KMT2AMEN1
Chloramben SCHEMBL55091 0.83 CYP3A4 (1.00) CYP3A4KDM4ETDP1KMT2AMEN1
SCHEMBL11652887 0.83 CYP3A4 (0.53) CYP3A4KDM4ETDP1KMT2AMEN1
Chloramben SCHEMBL29448826 0.83 CYP3A4 (1.00) CYP3A4KDM4ETDP1KMT2AMEN1
SCHEMBL14589553 0.81 CYP3A4 (0.47) CYP3A4KDM4ETDP1KMT2AMEN1
SCHEMBL10316093 0.81 CYP3A4 (0.68) CYP3A4KDM4ETDP1KMT2AMEN1
Chloramben SCHEMBL7422202 0.81 CYP3A4 (0.96) CYP3A4KDM4ETDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108530598-A A kind of ultralow dielectric properties halogen-free flameproof seal pressure material and preparation method thereof 广东省石油与精细化工研究院 2018-09-14 CN claimed
CN-108779352-A Low-emission liquid film for building sealing SIKA技术股份公司 2018-11-09 CN disclosed
CN-108699220-A The curing agent of low emission composition epoxy resin SIKA技术股份公司 2018-10-23 CN disclosed
CN-108699218-A Curable compositions SIKA技术股份公司 2018-10-23 CN disclosed
CN-108530598-A A kind of ultralow dielectric properties halogen-free flameproof seal pressure material and preparation method thereof 广东省石油与精细化工研究院 2018-09-14 CN disclosed
CN-104870509-B Curing agents for low emission epoxy resin products SIKA技术股份公司 2018-06-08 CN disclosed
CN-107922585-A Low Emission Epoxy Resin Composition SIKA技术股份公司 2018-04-17 CN disclosed
CN-103917573-B The curing agent with aromatic amine for epoxy resin SIKA技术股份公司 2018-04-10 CN disclosed
CN-104854077-B Amine for low emission epoxy resin product SIKA技术股份公司 2018-01-09 CN disclosed
CN-107532055-A Cold-curing epoxy primer or adhesive SIKA技术股份公司 2018-01-02 CN disclosed
CN-104884496-B Curing agent for low emission epoxy resin product SIKA技术股份公司 2017-12-29 CN disclosed
CN-107428911-A Amine for fast-curing epoxy resin composition SIKA技术股份公司 2017-12-01 CN disclosed
CN-107108836-A Two-component composition SIKA技术股份公司 2017-08-29 CN disclosed
CN-107001577-A Polyurea composition SIKA技术股份公司 2017-08-01 CN disclosed
CN-106715515-A Amines for low emission epoxy resin compositions SIKA技术股份公司 2017-05-24 CN disclosed
WO-2017050994-A1 DYE COMPOSITION USING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE PARTICULAR AMINOBENZENE COUPLER, PROCESSES AND DEVICE L'OREAL (FR) 2017-03-30 WO disclosed
EP-1224233-B1 METHOD FOR PRODUCING PREPOLYMERS CONTAINING ISOCYANATE END GROUPS, INCORPORATING A SMALL PROPORTION OF BASE ISOCYANATES BAYER AG (DE) 2003-11-05 EP disclosed
EP-1224233-A1 METHOD FOR PRODUCING PREPOLYMERS CONTAINING ISOCYANATE END GROUPS, INCORPORATING A SMALL PROPORTION OF BASE ISOCYANATES Bayer Aktiengesellschaft (DE) 2002-07-24 EP disclosed
WO-2001014443-A1 METHOD FOR PRODUCING PREPOLYMERS CONTAINING ISOCYANATE END GROUPS, INCORPORATING A SMALL PROPORTION OF BASE ISOCYANATES BAYER AKTIENGESELLSCHAFT (DE) 2001-03-01 WO disclosed