SCHEMBL7190882

SCHEMBL7190882

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1N2C(=O)c1ccc(C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 5/20 0.41
BCHE P06276 1/20 0.41
CACNA1H O95180 1/20 0.40
CACNA1B Q00975 1/20 0.40
POLB P06746 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 2/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435150 0.88 P2RX4 (0.56) P2RX4CACNA1HCACNA1BALDH1A1MAPT
SCHEMBL7007991 0.88 P2RX4 (0.56) P2RX4CACNA1HCACNA1BALDH1A1MAPT
SCHEMBL10617141 0.85 P2RX4 (0.63) P2RX4CACNA1HCACNA1BMAPTSMN1; SMN2
SCHEMBL8924419 0.84 BCHE (0.46) P2RX4BCHECACNA1HCACNA1BPOLB
SCHEMBL13138312 0.83 CACNA1B (0.55) CACNA1HCACNA1BALDH1A1MAPTHPGD
SCHEMBL8926849 0.83 CACNA1B (0.52) CACNA1HCACNA1BALDH1A1HPGDSMN1; SMN2
SCHEMBL9354682 0.82 P2RX4 (0.49) P2RX4CACNA1HCACNA1BALDH1A1MAPT
SCHEMBL9009191 0.82 MEN1 (0.57) BCHEPOLBALDH1A1MAPTNPC1
SCHEMBL9009797 0.81 MAPT (0.48) P2RX4POLBALDH1A1MAPTHPGD
SCHEMBL8926804 0.80 CACNA1B (0.52) CACNA1HCACNA1BALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8011428-A None JP disclosed
US-6586364-B2 Shell walls; liquid coloring PENTAX CORPORATION (JP) 2003-07-01 US disclosed
JP-H0811428-A PRESSURE-SENSITIVE RECORDING MATERIAL NEW OJI PAPER CO LTD 1996-01-16 JP disclosed