SCHEMBL8924419

SCHEMBL8924419

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1N2C(=O)c1ccc(OC(C)=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
CACNA1H O95180 2/20 0.43
CACNA1B Q00975 2/20 0.43
KMT2A Q03164 3/20 0.41
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.38
P2RX4 Q99571 3/20 0.37
ELANE P08246 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13138312 0.85 CACNA1B (0.55) CACNA1HCACNA1BKMT2AMEN1
SCHEMBL7190882 0.84 P2RX4 (0.41) BCHECACNA1HCACNA1BKMT2ANPC1
SCHEMBL8926849 0.84 CACNA1B (0.52) CACNA1HCACNA1BKMT2AMEN1
SCHEMBL29435150 0.83 P2RX4 (0.56) CACNA1HCACNA1BKMT2ANPC1RAB9A
SCHEMBL7007991 0.83 P2RX4 (0.56) CACNA1HCACNA1BKMT2ANPC1RAB9A
SCHEMBL8926075 0.82 CACNA1B (0.52) CACNA1HCACNA1BKMT2AMEN1
SCHEMBL8926804 0.82 CACNA1B (0.52) CACNA1HCACNA1BKMT2AMEN1
SCHEMBL10617141 0.80 P2RX4 (0.63) CACNA1HCACNA1BKMT2AP2RX4MEN1
SCHEMBL9009797 0.79 MAPT (0.48) KMT2APOLBP2RX4MEN1
SCHEMBL9354682 0.77 P2RX4 (0.49) CACNA1HCACNA1BKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102924454-B Synthetic method of entecavir SUZHOU WELL BRIDGE BIOLOG TECHNOLOGY CO LTD 2015-07-22 CN disclosed
CN-102924454-A Synthetic method of entecavir SUZHOU WELL BRIDGE BIOLOG TECHNOLOGY CO LTD 2013-02-13 CN disclosed
US-5663042-A LIGHT AND HEAT SENSITIVE SILVER HALIDE ELEMENNTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-02 US disclosed
EP-0689685-A1 BALLASTED LEUCO DYES AND PHOTOTHERMOGRAPHIC ELEMENT CONTAINING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-03 EP disclosed
EP-0681210-A1 Novel developing agents for (photo) thermographic systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-08 EP disclosed
US-5424183-A Stable color images, high resolution MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-13 US disclosed
US-5412088-A 6-O-substituted guanosine derivatives RUTGERS, THE STATE UNIVERSITY (US) 1995-05-02 US disclosed
WO-1994022055-A1 BALLASTED LEUCO DYES AND PHOTOTHERMOGRAPHIC ELEMENT CONTAINING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-29 WO disclosed