Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 7/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057077 | 0.92 | CYP2D6 (0.41) | CYP2D6THRBHSD17B10MAPTCA2 | |
| SCHEMBL3901023 | 0.90 | TLR4 (0.42) | CYP2D6THRBHSD17B10TLR4LY96 | |
| SCHEMBL15135027 | 0.90 | TLR4 (0.36) | TLR4LY96 | |
| SCHEMBL7057072 | 0.89 | CYP2D6 (0.42) | CYP2D6THRBHSD17B10MAPTCA2 | |
| SCHEMBL358376 | 0.88 | TLR4 (0.44) | TLR4LY96 | |
| SCHEMBL10447319 | 0.88 | TLR4 (0.44) | TLR4LY96 | |
| SCHEMBL15135028 | 0.88 | LGALS8 (0.36) | TLR4MAPT | |
| SCHEMBL8038328 | 0.85 | CYP2D6 (0.47) | CYP2D6THRBHSD17B10MAPTCA2 | |
| SCHEMBL19138246 | 0.83 | TLR4 (0.46) | TLR4LY96 | |
| SCHEMBL25053622 | 0.83 | TLR4 (0.42) | TLR4LY96MAPTCA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620433-B2 | Dispersible and soluble galenic paracetamol formulation, method for its preparation and its applications | LABORATORIOS BELMAC, S.A. (ES) | 2003-09-16 | — | — | US | claimed |