Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535227 | 0.74 | PIM1 (0.36) | LMNA | |
| SCHEMBL3024917 | 0.70 | — | — | |
| SCHEMBL11902996 | 0.64 | GLA (0.33) | LMNAMAPTPOLBPKM | |
| SCHEMBL7198143 | 0.64 | LMNA (0.32) | LMNA | |
| SCHEMBL29222497 | 0.62 | TNFSF11 (0.32) | LMNA | |
| SCHEMBL8820561 | 0.62 | PIM1 (0.32) | LMNAKDM4E | |
| SCHEMBL319885 | 0.62 | LMNA (0.31) | LMNAKDM4E | |
| SCHEMBL31648648 | 0.61 | — | — | |
| SCHEMBL11610762 | 0.61 | CYP3A4 (0.39) | LMNACYP3A4 | |
| SCHEMBL72231 | 0.61 | MAPT (0.59) | LMNAMAPTKDM4EMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030235777-A1 | Mixing resin obtained by polymerizing 1-vinyl-3-esterphenyl compound with one or more monomers and treating the polymer to provide meta-hydroxyphenyl repeat units with photoactive component | SHIPLEY COMPANY, L.L.C. | 2003-12-25 | — | — | US | claimed |
| US-20030235777-A1 | Mixing resin obtained by polymerizing 1-vinyl-3-esterphenyl compound with one or more monomers and treating the polymer to provide meta-hydroxyphenyl repeat units with photoactive component | SHIPLEY COMPANY, L.L.C. | 2003-12-25 | — | — | US | disclosed |