SCHEMBL7194607

SCHEMBL7194607

Nc1ccc(Oc2ccc(C(F)(F)F)c(Oc3ccc(N)cc3C(F)(F)F)c2)c(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
AR P10275 11/20 0.40
L3MBTL1 Q9Y468 3/20 0.38
RAB9A P51151 1/20 0.38
PLA2G7 Q13093 1/20 0.38
KIF11 P52732 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
HTR2A P28223 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8137340 0.95 GLA (0.43) GLAPOLBGAATSHRAR
SCHEMBL8139607 0.95 GAA (0.50) GLAPOLBGAATSHRAR
SCHEMBL8145930 0.92 GAA (0.46) GLAPOLBGAATSHRAR
SCHEMBL29352455 0.88 TSHR (0.53) GLAPOLBGAATSHRAR
SCHEMBL649657 0.88 TSHR (0.53) GLAPOLBGAATSHRAR
SCHEMBL29945087 0.88 GLA (0.43) GLAPOLBGAATSHRAR
SCHEMBL3551704 0.88 GLA (0.43) GLAPOLBGAATSHRAR
SCHEMBL7181956 0.87 GLA (0.46) GLAPOLBGAATSHRAR
SCHEMBL7187793 0.86 TSHR (0.52) GLAPOLBGAATSHRAR
SCHEMBL1352801 0.86 TSHR (0.52) GLAPOLBGAATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed