SCHEMBL649657

SCHEMBL649657

Nc1ccc(Oc2ccc(Oc3ccc(N)cc3C(F)(F)F)cc2)c(C(F)(F)F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
GAA P10253 2/20 0.53
GLA P06280 1/20 0.53
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 6/20 0.43
MAPT P10636 5/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MITF O75030 1/20 0.39
GFER P55789 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39
AR P10275 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352455 1.00 TSHR (0.53) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL7187793 0.98 TSHR (0.52) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL1352801 0.98 TSHR (0.52) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL29448858 0.98 TSHR (0.52) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL651384 0.95 TSHR (0.48) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL9680721 0.95 TSHR (0.48) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL2791640 0.93 TSHR (0.47) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL5583856 0.93 L3MBTL1 (0.53) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL8139607 0.93 GAA (0.50) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL22175023 0.92 GAA (0.53) TSHRGAAGLAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102770-A1 CROSS-LINKED POLYIMIDE LITHIUM BATTERY SEPARATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 亚安顶材有限公司 2026-05-21 WO claimed
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
US-12619010-B2 Optical multilayer structure and method of manufacturing the same SK INNOVATION CO., LTD. (KR) 2026-05-05 US claimed
US-12411267-B2 Optical multilayer structure and method for manufacturing the same SK INNOVATION CO., LTD. (KR) 2025-09-09 US claimed
US-20250054696-A1 THIN FILM CAPACITOR Meta Synthesis Materials Co., Ltd. (TW) 2025-02-13 US claimed
US-20240336738-A1 RESIN COMPOSITION, POLYIMIDE PREPARATION METHOD AND RELATED PRODUCTS AAC TECHNOLOGIES (NANJING) CO., LTD. (CN) 2024-10-10 US claimed
WO-2024207567-A1 RESIN COMPOSITION, POLYIMIDE PREPARATION METHOD, AND RELATED PRODUCT 瑞声科技(南京)有限公司 2024-10-10 WO claimed
US-12024594-B2 Multifunctional materials for temporary bonding BREWER SCIENCE, INC. (US) 2024-07-02 US claimed
US-20240150524-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-05-09 US claimed
US-20240026155-A1 Polyamideimide Film and Optical Multilayer Structure Comprising the Same SK INNOVATION CO., LTD. (KR) 2024-01-25 US claimed
US-20130011642-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2013-01-10 US claimed
US-20120305484-A1 Thermally Rearranged (TR) Polymers as Membranes for Ethanol Dehydration BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-12-06 US claimed
US-20120244330-A1 AROMATIC POLYAMIDE FILMS FOR TRANSPARENT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. 2012-09-27 US claimed
US-7820253-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS (US) 2010-10-26 US claimed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US claimed
WO-2009045537-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2009-04-09 WO claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619010-B2 Optical multilayer structure and method of manufacturing the same UHRF1, ASH2L, UBAP2L TSHR 1571/4885GAA 4382/4885GLA 1544/4885
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same PUF60, ZW10, UBAP2L TSHR 2919/4885GAA 4415/4885GLA 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.