Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496590 | 0.89 | — | — | |
| SCHEMBL8357677 | 0.89 | — | — | |
| SCHEMBL8357678 | 0.89 | — | — | |
| SCHEMBL10730624 | 0.84 | — | — | |
| SCHEMBL17683796 | 0.84 | — | — | |
| SCHEMBL11705995 | 0.82 | — | — | |
| SCHEMBL13729177 | 0.80 | — | — | |
| SCHEMBL8351515 | 0.79 | — | — | |
| SCHEMBL6258110 | 0.78 | DNM1 (0.36) | CYP3A4DNM1ALDH1A1TDP1 | |
| SCHEMBL19736674 | 0.78 | DNM1 (0.39) | CYP3A4DNM1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921161-B1 | Flame retardant polyetherimide resin composition | GEN ELECTRIC (US) | 2003-10-08 | — | — | EP | disclosed |