SCHEMBL7196027

SCHEMBL7196027

COC(O)N(c1nc(N(C(O)OC)C(O)OC)nc(N(C(O)OC)C(O)OC)n1)C(O)OC

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
BLM P54132 1/20 0.30
CREBBP Q92793 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874651 0.72 LMNA (0.33) LMNACYP1A2THRBBLMCREBBP
SCHEMBL2115018 0.70 LMNA (0.32) LMNACYP1A2THRBBLMCREBBP
SCHEMBL311197 0.69
SCHEMBL275457 0.69 LMNA (0.35) LMNACYP1A2THRBBLMCREBBP
SCHEMBL8656372 0.67 LMNA (0.32) LMNACYP1A2THRBBLMCREBBP
SCHEMBL8861765 0.61
SCHEMBL32679727 0.61 LMNA (0.39) LMNACYP1A2THRBBLMCREBBP
SCHEMBL15789477 0.60 MAPT (0.32) LMNA
SCHEMBL4269410 0.56 LMNA (0.40) LMNACYP1A2THRBBLMCREBBP
SCHEMBL16090137 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527976-B1 A polymeric backbone, at least two terminal curing functional groups, at least one oxygen scavenging cyclic moiety that is pendant to backbone and comprises a ring having from 5 to 9 carbons atoms and at least one double bond CHENRON PHILLIPS CHEMICAL COMPANY LP 2003-03-04 US claimed
US-6527976-B1 A polymeric backbone, at least two terminal curing functional groups, at least one oxygen scavenging cyclic moiety that is pendant to backbone and comprises a ring having from 5 to 9 carbons atoms and at least one double bond CHENRON PHILLIPS CHEMICAL COMPANY LP 2003-03-04 US disclosed
US-4609717-A LOW VISCOSITY POLYETHER AND POLYETHERLACTONE COPOLYMERS PPG INDUSTRIES, INC. (US) 1986-09-02 US disclosed
US-4569966-A POLYURETHANE, POLYESTERURETHANE , POLYUREA PARTICLES IN DISPERSION; USED IN COATING COMPOSITION PPG INDUSTRIES, INC. (US) 1986-02-11 US disclosed
US-4419407-A POLYESTERPOLYOL, POLYURETHANEPOLYOL, CURING AGENT, FLEXIBILITY PPG INDUSTRIES, INC. (US) 1983-12-06 US disclosed
US-4410668-A CYCLOALIPHATIC POLYESTERPOLYOL, POLYURETHANEPOLYOL, CURING AGENT PPG INDUSTRIES, INC. (US) 1983-10-18 US disclosed
US-4154891-A POLYMERIC POLYOL, AMINE-ALDEHYDE CONDENSATE PPG INDUSTRIES, INC. (US) 1979-05-15 US disclosed
US-4075141-A IMPROVED FILM BUILD PPG INDUSTRIES, INC. (US) 1978-02-21 US disclosed
US-4029621-A COATINGS PPG INDUSTRIES, INC. (US) 1977-06-14 US disclosed