Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130370 | 0.85 | POLB (0.49) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL17364296 | 0.81 | PDE4A (0.46) | MEN1KMT2ALMNATDP1POLB | |
| SCHEMBL17364325 | 0.81 | KMT2A (0.44) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL16785946 | 0.81 | PDE4A (0.42) | MEN1KMT2ALMNASPHK1PDE4A | |
| SCHEMBL8058913 | 0.80 | PDE4A (0.48) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL30498890 | 0.80 | PDE4A (0.44) | RAB9AMEN1KMT2ALMNACA12 | |
| SCHEMBL29051509 | 0.80 | PDE4A (0.44) | RAB9AMEN1KMT2ALMNACA12 | |
| SCHEMBL11114702 | 0.78 | KMT2A (0.55) | RAB9AMEN1KMT2APKMCYP2C19 | |
| SCHEMBL16788260 | 0.78 | KMT2A (0.55) | RAB9AMEN1KMT2APKMCYP2C19 | |
| SCHEMBL18872551 | 0.78 | PDE4A (0.40) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6587845-B1 | Method and apparatus for identification and optimization of bioactive compounds using a neural network | Braunheim, Benjamin B. | 2003-07-01 | — | — | US | disclosed |