SCHEMBL7196282

SCHEMBL7196282

CCCCCCCCCCCCCCCCCCc1ccccc1OP(O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.58
THRB P10828 1/20 0.58
LIPG Q9Y5X9 1/20 0.53
ALOX5 P09917 1/20 0.51
PTGS2 P35354 1/20 0.51
PPARA Q07869 3/20 0.49
PPARG P37231 2/20 0.47
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887815 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL5224716 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL30380227 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL4443988 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL28530051 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL30380290 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL4445684 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL247534 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL11674760 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2
SCHEMBL8802110 1.00 THRA (0.58) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739942-B1 RESIN COMPOSITION EXCELLENT IN IMPACT RESISTANCE KANEGAFUCHI CHEMICAL IND (JP) 2003-05-07 EP disclosed
US-6136918-A (METH)ACRYLIC ACID, CROTONIC AND/OR ITACONIC ACID AND ALKYL (METH)ACRYLATE MONOMERS; IMPACT STRENGTH KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-10-24 US disclosed
EP-0870799-A1 RUBBER LATEX, GRAFT COPOLYMER, AND THERMOPLASTIC RESIN COMPOSITION KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-10-14 EP disclosed
US-5798414-A GRAFT COPOLYMER SUPERIOR IN MOLDING, HEAT RESISTANCE, GLOSS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-08-25 US disclosed
EP-0739942-A1 RESIN COMPOSITION EXCELLENT IN IMPACT RESISTANCE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-10-30 EP disclosed
EP-0029426-A1 MINERAL FIBER REINFORCED POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 1981-06-03 EP disclosed
EP-0029426-A4 MINERAL FIBER REINFORCED POLYCARBONATE. GEN ELECTRIC (US) 1981-05-15 EP disclosed
WO-1980002691-A1 MINERAL FIBER REINFORCED POLYCARBONATE GEN ELECTRIC 1980-12-11 WO disclosed