SCHEMBL7196290

SCHEMBL7196290

CSCOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.65
SLC28A2 O43868 1/20 0.65
SLC29A1 Q99808 1/20 0.65
SLC28A3 Q9HAS3 1/20 0.65
P2RY6 Q15077 9/20 0.63
P2RY2 P41231 13/20 0.62
P2RY4 P51582 7/20 0.62
P2RY14 Q15391 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13116348 0.90 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL13435032 0.90 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL12259056 0.87 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL121732 0.87 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL16148484 0.86 SLC28A1 (0.65) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1532521 0.86 SLC28A1 (0.74) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL6879979 0.85 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL11992613 0.85 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL17014892 0.85 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL912472 0.85 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002512794-A 2002-05-08 JP claimed
EP-1073732-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 2001-02-07 EP claimed
WO-1999055857-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-11-04 WO claimed
US-6509460-B1 Contacting the modified nucleotide triphosphate with a mixture comprising a nucleic acid template, an RNA polymerase enzyme, and an enhancer of modified nucleotide triphosphate incorporation RIBOZYME PHARMACEUTICALS, INC. 2003-01-21 US disclosed
US-6482932-B1 Nucleoside triphosphates and their incorporation into oligonucleotides RIBOZYME PHARMACEUTICALS, INCORPORATED 2002-11-19 US disclosed
EP-1073732-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 2001-02-07 EP disclosed
WO-1999055857-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-11-04 WO disclosed
WO-1998050530-A9 ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE RIBOZYME PHARM INC (US) 1999-03-25 WO disclosed