Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.65 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 13/20 | 0.64 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.63 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.62 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15515639 | 0.90 | P2RY2 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL17728069 | 0.89 | P2RY14 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL5574933 | 0.89 | SLC28A1 (0.62) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL121732 | 0.87 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL12259056 | 0.87 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL5616899 | 0.87 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL7196290 | 0.86 | SLC28A1 (0.65) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL1532521 | 0.86 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL13435032 | 0.85 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL13116348 | 0.85 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964234-A1 | HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA | Moderna Therapeutics, Inc. (US) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014164253-A1 | HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA | MODERNA THERAPEUTICS, INC. (US) | 2014-10-09 | — | — | WO | disclosed |