Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069016 | 1.00 | ALDH1A1 (0.65) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL9685695 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL7070247 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL7070248 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL7072637 | 0.83 | POLB (0.56) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL7072634 | 0.83 | POLB (0.56) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL2391096 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL1568318 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL1571210 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAGAATSHR | |
| SCHEMBL9685718 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586602-B2 | CD antigen antagonists such as N-(methanesulfonyl)-L-prolyl-L-phenylalanine and prodrugs used as antiinflammatory agents | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2003-07-01 | — | — | US | disclosed |
| US-6362341-B1 | ANTIINFLAMMATORY AGENTS | ATHENA NEUROSCIENCES, INC. | 2002-03-26 | — | — | US | disclosed |