Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594732 | 0.88 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL30676217 | 0.87 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL28075702 | 0.87 | MAPT (0.50) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL29534282 | 0.84 | HPGD (0.61) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL14691594 | 0.84 | HPGD (0.61) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL655856 | 0.84 | MEN1 (0.56) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL10033297 | 0.84 | HTT (0.50) | MAPTSMN1; SMN2PKMHTTALDH1A1 | |
| SCHEMBL2061142 | 0.83 | KMT2A (0.50) | MAPTSMN1; SMN2AKR1C3AKR1C2MPO | |
| SCHEMBL12031278 | 0.83 | PDK1 (0.63) | MAPTPKMHTTALDH1A1RAB9A | |
| SCHEMBL1008274 | 0.83 | HTT (0.49) | MAPTSMN1; SMN2PKMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600016-B1 | Solid support for use in the biosynthesis of combinatorial libraries | ADVANCED SYNTECH LLC | 2003-07-29 | — | — | US | disclosed |